Interactions Between PE-22-28 and Nerve Cells
PE-22-28 is a 7-amino-acid peptide derived from the degradation products of spadin (PE 12-28), which itself originates from the post-translational maturation of sortilin. Researchers have posited that the peptide may act primarily through a TREK-1 blockade, and data...
GHK-Cu Peptide: A Review of Mechanisms and Studies
GHK-Cu is a tripeptide-copper complex formed by the chelation of glycyl-L-histidyl-L-lysine (GHK) with a divalent copper ion (Cu²+). The GHK sequence is posited to arise endogenously from the proteolytic breakdown of collagen. Researchers believe it may potentially be...
Epigenetic Potential of Vesilute
Vesilute or Vesilut appears to be one of Khavinson’s peptides, which are considered bioregulators that may interact with specific parts of DNA and support gene expression. It has the sequence of Glu-Asp (Glutamic Acid - Aspartic Acid), or ED for short. This sequence...
KED Potential Actions in Different Models of Cellular Aging
KED (Vesugen) is posited to be a short peptide that may act as a cell-regulating bioregulator with actions on differentiation, repair, and functional maintenance in aging cells. The peptide is defined as one of Khavinson’s peptides, and it is studied primarily by the...
The Potential of Anabolism and Synergism in a Sermorelin & Ipamorelin Blend
Sermorelin and Ipamorelin are research peptides that may have synergistic actions when blended, as they may stimulate the release of growth hormone (hGH) from pituitary cells via complementary pathways. Sermorelin appears to be analogous to the endogenous GHRH, which...
Sermorelin & GHRP-2 Synergistic Potential on Growth Hormone and IGF-1 Synthesis
Sermorelin and GHRP-2 are two peptides researched for their potential to stimulate the release of growth hormone (hGH) from pituitary cells. Each of these peptides appears to mediate this potential through a distinct receptor system. Sermorelin appears to interact...
Sermorelin: Potential Interactions with Different Hormone-Producing Cells
Sermorelin is a research peptide considered to be the shortest functional analog of the endogenous growth hormone-releasing hormone (GHRH). For context, GHRH has a 44 amino acid structure posited to be the main hormone that interacts with the cells responsible for the...
FOXO4-DRI Peptide Potential Interactions with Aged Cell Cultures
FOXO4-DRI is a synthetic peptide that is actively researched regarding its potential to induce programmed cell death in aged cells, and thus reduce the burden that aged cells pose on different tissues. Apparently, the peptide achieves that by mimicking a part of the...
Palmitoyl Tetrapeptide-7 Potential Actions On Dermal Cells and Collagen Synthesis
Palmitoyl Tetrapeptide-7, also referred to as Pal-GQPR, is considered a tetrapeptide that may “stimulate collagen renewal and inhibit collagen degradation” in mammalian models according to the available research.(1) This tetrapeptide is described as a palmitoylated...